Spinal cord and infratentorial lesions in radiologically isolated syndrome are associated with decreased retinal ganglion cell/inner plexiform layer thickness.
Angeliki G FilippatouThomas ShoemakerMegan EschMadiha QutabNatalia Gonzalez-CalditoJerry L PrinceEllen M MowryPeter A CalabresiShiv SaidhaElias S SotirchosPublished in: Multiple sclerosis (Houndmills, Basingstoke, England) (2018)
The presence of SC or IT lesions in RIS may be associated with retinal neuro-axonal loss, supporting the presence of more disseminated disease.