The frequency of non-motor symptoms in SCA3 and their association with disease severity and lifestyle factors.

Holger HengelPeter MartusJennifer FaberPaola GiunitHector Garcia-MorenoNita SolankyThomas KlockgetherKathrin ReetzBart P van de WarrenburgMagda M SantanaPatrick SilvaInês CunhaLuís Pereira de AlmeidaDagmar TimmannJon InfanteJeroen de VriesManuela LimaPaula PiresKhalaf BusharaHeike JacobiChiadi OnyikeJeremy D SchmahmannJeannette Hübener-SchmidMatthis Synofziknull nullLudger Schöls

Published in: Journal of neurology (2022)

This study revealed a clear association between disease severity and NMS, likely driven by the progression of the widespread neurodegenerative process. Associations between lifestyle and NMS can probably be attributed to the influence of NMS on lifestyle.

Keyphrases

metabolic syndrome
weight loss
physical activity
cardiovascular disease
single cell
type diabetes