Draft genome sequences of Hirudo medicinalis and salivary transcriptome of three closely related medicinal leeches.

Vladislav V BabenkoOleg V PodgornyValentin A ManuveraArtem S KasianovAlexander I ManolovEkaterina N GrafskaiaDmitriy A ShirokovAlexey S KurdyumovDmitriy V VinogradovAnastasia S NikitinaSergey I KovalchukNickolay A AnikanovIvan O ButenkoOlga V PobegutsDaria S MatyushkinaDaria V RakitinaElena S KostryukovaVictor G ZgodaIsolda P BaskovaVladimir M TrukhanMikhail S GelfandVadim M GovorunHelgi B SchiöthVassili N Lazarev

Published in: BMC genomics (2020)

Here we report a genome draft of Hirudo medicinalis and describe identification of novel salivary proteins and new homologs of genes encoding known anticoagulants in transcriptomes of three medicinal leech species. Our data provide new insights in genetics of blood-feeding lifestyle in leeches.

Keyphrases

genome wide
bioinformatics analysis
single cell
dna methylation
metabolic syndrome
electronic health record
rna seq
gene expression
cardiovascular disease
physical activity
genetic diversity
big data
weight loss