Chronic nausea and orthostatic intolerance: Diagnostic utility of orthostatic challenge duration, Nausea Profile Questionnaire, and neurohumoral measures.
Ashley L WagonerSally E TarbellHossam A ShaltoutDebra I DizDebra E Weese-MayerJohn E FortunatoPublished in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2018)
In children with chronic nausea and OI, longer duration HUT elicited higher frequency of abnormal tilt testing and orthostatic-induced nausea. The Nausea Profile Questionnaire predicted the orthostatic response to tilt testing. Exaggerated vasopressin release differentiated patients with HUT-induced nausea (vs those without nausea), suggesting a possible mechanism for chronic nausea in childhood.