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Unraveling the shared genetics of common epilepsies and general cognitive ability.

Naz KaradagEspen HagenAlexey A ShadrinDennis van der MeerKevin Sean O'ConnellZillur RahmanGleda KutrolliNadine ParkerShahram BahramiVera FominykhKjell HeuserErik TaubøllTorill UelandNiels Eiel SteenSrdjan DjurovicAnders M DaleOleksandr FreiOle Andreas AndreassenOlav B Smeland
Published in: medRxiv : the preprint server for health sciences (2024)
Our study demonstrates a substantial genetic basis shared between epilepsies and COG and identifies novel overlapping genomic loci. Enhancing our understanding of the relationship between epilepsies and COG may lead to the development of novel comorbidity-targeted epilepsy treatments.
Keyphrases
  • genome wide
  • copy number
  • dna methylation
  • drug delivery
  • genome wide association study
  • genome wide association