Integrated epigenetic biomarkers in circulating cell-free DNA as a robust classifier for pancreatic cancer.

Feng CaoAilin WeiXinlei HuYijing HeJun ZhangLin XiaKailing TuJue YuanZiheng GuoHongying LiuDan XieAng Li

Published in: Clinical epigenetics (2020)

Both 5mC and 5hmC biomarkers in cfDNA are effective in PDAC detection, and the 5mC-5hmC integrated model significantly improve the detection sensitivity.

Keyphrases

loop mediated isothermal amplification
real time pcr
label free
gene expression
dna methylation