Recognition and management of vitamin B12 deficiency: Report of four cases with oral manifestations.
Weslay Rodrigues da SilvaAndré Azevedo Dos SantosMariana Carvalho XerezEverton Freitas de MoraisPatrícia Teixeira de OliveiraÉricka Janine Dantas da SilveiraPublished in: Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry (2021)
Vitamins are organic compounds present in low concentrations in food, performing vital and specific cell metabolism functions. Vitamin B12 is essential for red blood cell formation in the bone marrow and its deficiency is caused, mainly, by gastrointestinal malabsorption. In addition to systemic manifestations, oral signs and symptoms have also been associated to this condition such as glossitis, papillary atrophy, painful erythema areas, burning sensation, dysgeusia, lingual paresthesia and itching. This study aims to report four cases of oral manifestations caused by vitamin B12 deficiency. All patients presented oral mucosa lesions. Vitamin B12 deficiency was diagnosed based in clinical characteristics and complementary exams. Oral supplementation for vitamin B12 deficiency was conducted/realized in three patients, while one patient was treated with parenteral doses. All of them showed partial or total remission of the signs and symptoms.
Keyphrases
- end stage renal disease
- bone marrow
- newly diagnosed
- ejection fraction
- chronic kidney disease
- red blood cell
- prognostic factors
- peritoneal dialysis
- mesenchymal stem cells
- replacement therapy
- rheumatoid arthritis
- patient reported outcomes
- risk assessment
- systemic lupus erythematosus
- physical activity
- disease activity
- smoking cessation
- human health
- depressive symptoms