Comprehensive and Accurate Molecular Profiling of Breast Cancer through mRNA Expression of ESR1 , PGR , ERBB2 , MKI67 , and a Novel Proliferation Signature.

Anne-Sophie WegscheiderJoanna GorniakSara RollinsonLeanne GoughNavdeep DhaliwalAgustin GuardiolaAnna GasiorDenise HelmerZoe PounceAxel Niendorf

Published in: Diagnostics (Basel, Switzerland) (2024)

By assessing the concordance with the results obtained through IHC, we sought to demonstrate the reliability and utility of the kit for precise BC subtyping. Our findings suggest that the kit provides a highly precise and accurate quantitative assessment of BC biomarkers.

Keyphrases

high resolution
signaling pathway
tyrosine kinase
single cell
single molecule
mass spectrometry
young adults
childhood cancer