Are We Eating Our Way to Prostate Cancer-A Hypothesis Based on the Evolution, Bioaccumulation, and Interspecific Transfer of miR-150.
Venkatesh VaidyanathanVetrivhel KrishnamoorthyNishi KarunasingheAnower JabedRadha PallatiChi Hsiu-Juei KaoAlice WangGareth MarlowLynnette Robin FergusonPublished in: Non-coding RNA (2016)
MicroRNAs (miRNAs) are well established epigenetic modifiers. There is a lot of work being done to identify the evolutionary transfer of miRNAs both at intra- and interspecific levels. In this hypothesis-driven review, we have suggested a possible reason as to why miR-150 can be a promising diagnostic biomarker for prostate cancer using theories of evolution, bio-accumulation, and interspecific transfer of miRNAs.