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Early pregnancy protein multiplex screening reflects circulating and urinary divergences associated with the development of preeclampsia.

Margarita L Martinez-FierroClaudia Castruita-De La RosaIdalia Garza-VelozRosa M Cardiel-HernandezMarcela A Espinoza-JuarezIván Delgado-EncisoMaria E Castañeda-LopezEdith Cardenas-VargasFabiola Trejo-VázquezElma I Sotelo-HamRodrigo CastañedaMiguel A Cid-BaezJose M Ortiz-RodriguezLuis Octavio Solis-SanchezAngelica Garcia AvilesYolanda Ortiz-Castro
Published in: Hypertension in pregnancy (2018)
The proteins sEGFR, HGF, ANG-2, sFASL, IL-6, PLGF, VEGF-A, PRL, TGF-α FGF-b, sHER2/Neu sIL-6Rα, ENG, uPA, and insulin-like growth factor binding protein 1 (IGFBP-1), were predictive of the development of preeclampsia and their use as markers for this disease should be considered.
Keyphrases
  • binding protein
  • early onset
  • endothelial cells
  • transforming growth factor
  • angiotensin ii
  • high throughput
  • vascular endothelial growth factor
  • epithelial mesenchymal transition