Proton Pump Inhibitor Use Affects Pseudarthrosis Rates and Influences Patient-Reported Outcomes.
John J ManganSrikanth Naga DiviJames C McKenzieJustin D StullWilliam ConawayDavid S CasperDhruv K C GoyalKristen J NicholsonMatthew S GalettaScott C WagnerI David KayeMark F KurdBarrett I WoodsKristen E RadcliffJeffery A RihnD Greg AndersonAlan S HilibrandAlexander R VaccaroGregory D SchroederChristopher K KeplerPublished in: Global spine journal (2019)
PPI use was found to be a significant predictor of clinically diagnosed pseudarthrosis following ACDF surgery. Furthermore, clinically diagnosed pseudarthrosis negatively influenced improvement in PCS-12 scores.