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Alterations of contralesional hippocampal subfield volumes and relations to cognitive functions in patients with unilateral stroke.

Juan-Juan LuXiang-Xin XingJiao QuJia-Jia WuMou-Xiong ZhengXu-Yun HuaJian-Guang Xu
Published in: Brain and behavior (2024)
Unilateral stroke caused volumetric differences in different hippocampal subfields contralesionally, which correlated to cognitive impairment. RHS leads to greater volumetric reduction in the whole contralesional hippocampus and specific subfields (hippocampal tail, CA1, ML, GC-ML-DG, CA3, and CA4) compared to LHS. These changes are correlated with cognitive impairments, potentially due to disrupted neural pathways and interhemispheric communication.
Keyphrases
  • cerebral ischemia
  • cognitive impairment
  • subarachnoid hemorrhage
  • atrial fibrillation
  • blood brain barrier
  • brain injury
  • protein kinase
  • temporal lobe epilepsy
  • high resolution