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Piperine alleviates nonalcoholic steatohepatitis by inhibiting NF-κB-mediated hepatocyte pyroptosis.

Suye RanLingyu SongHong YangJiangnan YuYunhuan ZhenQi Liu
Published in: PloS one (2024)
Pip ameliorates NASH progression, and the therapeutical effect was associated with inhibition of hepatocyte pyroptosis induced by NF-κB.
Keyphrases
  • signaling pathway
  • lps induced
  • nlrp inflammasome
  • pi k akt
  • liver injury
  • nuclear factor
  • mouse model
  • oxidative stress
  • inflammatory response
  • drug induced
  • immune response
  • toll like receptor
  • cell proliferation