Two rare cases of acute myeloid leukemia with t(8;16)(p11.2;p13.3) and 1q duplication: case presentation and literature review.

Meng LiuYuan RenXianfu WangXianglan LuMing LiYoung Mi KimShibo LiLijun Zhang

Published in: Molecular cytogenetics (2020)

A 1q duplication was detected in two of three AML patients with t(8;16)(p11.2;p13.3), suggesting that 1q duplication can be a recurrent event in AML patients with t(8;16). In concert with the findings of previous studies on similar patients, our work suggests that 1q duplication may also be an unfavorable prognostic factor of the disease.

Keyphrases

acute myeloid leukemia
prognostic factors
end stage renal disease
allogeneic hematopoietic stem cell transplantation
chronic kidney disease
case report
newly diagnosed
ejection fraction
peritoneal dialysis
patient reported outcomes
patient reported