Increased risk of cardiac ischaemia in a pan-European cohort of 36 205 childhood cancer survivors: a PanCareSurFup study.
Elizabeth Arnoldina Maria FeijenElvira C van DalenHeleen J H van der PalRaoul C ReulenDavid L WinterClaudia E KeuhniVera MorsellinoDaniela AlessiRodrigue S AllodjiJulliana ByrneEdit BardiZsuzsanna JakabDesiree GrabowStanislaw GarwiczNadia HaddyMomcilo JankovicPeter KaatschGill A LevittCecile M RonckersChristina SchinderaRoderick SkinnerLorna ZalatelLars HjorthWim J E TissingFlorent De VathaireMike M HawkinsLeontien C M Kremernull nullPublished in: Heart (British Cardiac Society) (2020)
In this very large European childhood cancer cohort, we found that by age 60 years, 1 in 18 CCS will develop a severe, life-threatening or fatal cardiac ischaemia, especially in lymphoma survivors and CCS treated with radiotherapy and chemotherapy increases the risk significantly.