Intrahepatic cholestasis of pregnancy and theory of inheritance of the disease. Literature review.

Weronika Niemyjska-DmochPrzemyslaw KosinskiPiotr WęgrzynKatarzyna LuterekAleksandra Jezela-Stanek

Published in: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians (2023)

Intrahepatic cholestasis during pregnancy is associated with a higher risk of prenatal and maternal complications. There are several new publications and guidelines on the detection and thresholds of intrahepatic cholestasis during pregnancy. However, the genetic background of this disease has rarely been investigated. This is a comprehensive review of the roles of genes in intrahepatic cholestasis during pregnancy.

Keyphrases

drug induced
genome wide
pregnancy outcomes
pregnant women
case report
mitochondrial dna
gene expression
risk factors
copy number
clinical practice
body mass index
loop mediated isothermal amplification
mass spectrometry
birth weight
high resolution
genome wide analysis