TFPI inhibits breast cancer progression by suppressing ERK/p38 MAPK signaling pathway.

Mengying XingYing YangJiaxue HuangYaqun FangYucui JinLingyun LiXiang ChenXiaoxia ZhuChangyan Ma

Published in: Genes & genomics (2022)

TFPI inhibited breast cancer cell proliferation, migration and invasion through inhibition of the ERK/p38 MAPK signaling pathway, suggesting that TFPI may serve as a novel prognostic biomarker and therapeutic target for breast cancer.

Keyphrases

signaling pathway
pi k akt
cell proliferation
epithelial mesenchymal transition
induced apoptosis
oxidative stress
childhood cancer