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Comparison of clinical efficiency between intra-articular injection of platelet-rich plasma and hyaluronic acid for osteoarthritis: a meta-analysis of randomized controlled trials.

Lili ChenShirong JinYunheng YaoSixian HeJinshen He
Published in: Therapeutic advances in musculoskeletal disease (2023)
In the treatment of OA, compared with HA, PRP performed better in the improvement of the patient's function. There was no significant difference in VAS and AEs between the two groups, and the safety was comparable. LP-PRP looked to be superior to LR-PRP in functional recovery, but there appeared to be no significant difference in pain relief between them. There was no significant difference between single PRP and triple PRP in the subgroup analysis.
Keyphrases
  • platelet rich plasma
  • hyaluronic acid
  • chronic pain
  • systematic review
  • knee osteoarthritis
  • rheumatoid arthritis
  • case report
  • pain management
  • study protocol
  • open label
  • double blind