Effectiveness and safety of intracranial events associated with the use of direct oral anticoagulants for atrial fibrillation: A systematic review and meta-analysis of 92 studies.

Paraschos Archontakis BarakakisWeijia LiDimitrios KalaitzoglouLazaros TzelvesApostolos ManolopoulosStefanos GiannopoulosGrigorios GiamouzisGeorge GiannakoulasApostolos BatsidisLeonidas PalaiodimosGeorge NtaiosGregory Y H LipDamianos G Kokkinidis

Published in: British journal of clinical pharmacology (2022)

Our study demonstrated significant differences in the risk of ischaemic stroke, TE/stroke and ICH associated with individual DOACs compared to both other DOACs and VKA.

Keyphrases

direct oral anticoagulants
atrial fibrillation
venous thromboembolism
oral anticoagulants
left atrial
catheter ablation
left atrial appendage
heart failure
percutaneous coronary intervention
case control
subarachnoid hemorrhage