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DPYD polymorphisms c.496A>G, c.2194G>A and c.85T>C and risk of severe adverse drug reactions in patients treated with fluoropyrimidine-based protocols.

Nada BožinaIvan BilićLana GanociLivija ŠimičevićStjepko PleštinaLucija LešnjakovićVladimir Trkulja
Published in: British journal of clinical pharmacology (2021)
DPYD c.496A>G and possibly c.2194G>A variants might need to be considered for inclusion in the DPYD genotyping panel.
Keyphrases
  • adverse drug
  • drug induced
  • electronic health record
  • copy number
  • emergency department
  • genome wide
  • early onset
  • high throughput
  • dna methylation
  • genetic diversity