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Pathology reduction and motor behavior improvement associated with ultrasound-mediated delivery of arctiin to the motor cortex in a mutant SOD1 mouse model of amyotrophic lateral sclerosis.

Ji ZhangKaili ChenYizhe ChenLingchen HuaSiping ChenXin ChenLiangyu ZouShupeng LiXifei YangYuanyuan Shen
Published in: Ultrasonics (2024)
These preliminary results indicated that the combined treatment of FUS/MB and arctiin exerted a potentially beneficial effect on neuromuscular function in the ALS disease.
Keyphrases
  • amyotrophic lateral sclerosis
  • mouse model
  • magnetic resonance imaging
  • computed tomography
  • ultrasound guided