The efficacy and safety of combinations of SGLT2 inhibitors and GLP-1 receptor agonists in the treatment of type 2 diabetes or obese adults: a systematic review and meta-analysis.

Man GuoJunling GuFangyuan TengJiao ChenXiumei MaQing ChenYueli PuZongzhe JiangYang LongYong Xu

Published in: Endocrine (2020)

SGLT2 inhibitors and GLP-1 agonists combination treatment improved glycemic control, reduced body weight, and decreased SBP without an increase in total adverse events or genital and urinary infections in patients with T2DM or obesity.

Keyphrases

type diabetes
glycemic control
body weight
weight loss
insulin resistance
metabolic syndrome
cardiovascular disease
blood glucose
adipose tissue
physical activity
combination therapy
body mass index
replacement therapy