Reduced Dose BCG in an Era of BCG Shortage: Real-World Experience from a Tertiary Cancer Centre.
Niyati LoboKelly K BreePatrick J HensleyGraciela M Nogueras-GonzalezPrasanth AbrahamNeema NavaiColin P DinneyAshish M KamatPublished in: BJU international (2021)
The use of 1/3D BCG was not associated with adverse oncological outcomes in a large cohort of patients receiving adequate BCG for intermediate- and high-risk NMIBC. Based on this real-world experience, risk-stratified split-vial dosing may represent a valuable approach for other institutions facing BCG shortages whilst also providing reassurance to patients who may be concerned about suboptimal outcomes.