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Reduced Dose BCG in an Era of BCG Shortage: Real-World Experience from a Tertiary Cancer Centre.

Niyati LoboKelly K BreePatrick J HensleyGraciela M Nogueras-GonzalezPrasanth AbrahamNeema NavaiColin P DinneyAshish M Kamat
Published in: BJU international (2021)
The use of 1/3D BCG was not associated with adverse oncological outcomes in a large cohort of patients receiving adequate BCG for intermediate- and high-risk NMIBC. Based on this real-world experience, risk-stratified split-vial dosing may represent a valuable approach for other institutions facing BCG shortages whilst also providing reassurance to patients who may be concerned about suboptimal outcomes.
Keyphrases
  • papillary thyroid
  • squamous cell carcinoma
  • adipose tissue
  • skeletal muscle
  • metabolic syndrome
  • young adults
  • radical prostatectomy
  • weight loss
  • glycemic control
  • adverse drug
  • insulin resistance
  • drug induced