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Hyperactivation and altered selection of B cells in patients with paediatric Sjogren's syndrome.

Alessandra BoniRebecca NicolaiIvan CaielloFrancesca MarinaroLuciapia FarinaDenise Pires MarafonRita CarsettiFabrizio De BenedettiClaudia BracagliaEmiliano Marasco
Published in: RMD open (2024)
Our results point to a hyperactivation of B cells in pSS. Current therapies do not seem to affect B cell abnormalities, suggesting that novel therapies targeting specifically B cell hyperactivation need to be implemented for paediatric patients.
Keyphrases
  • end stage renal disease
  • intensive care unit
  • newly diagnosed
  • chronic kidney disease
  • prognostic factors
  • peritoneal dialysis
  • cancer therapy