Childhood Acute Leukemias in Developing Nations: Successes and Challenges.
Marta Zapata-TarrésJuan Carlos BalandránRoberto Rivera-LunaRosana PelayoPublished in: Current oncology reports (2021)
A unique molecular epidemiology, late/low precision diagnosis, limited access to treatment, toxicity associated with therapy, continuous exposure to environmental risk factors, and the high frequency of early relapses are some of the factors cooperating to low rates of survival in low-to-medium-income countries. Deliberative dialogues and exhaustive programs have emerged as promising means of advancing evidence-informed policy, by providing a structured forum for key stakeholders to integrate scientific and pragmatic knowledge about complex health concerns. A system-wide strategy based on the comprehensive leukemia identity is essential for a meaningful decline in early childhood mortality.
Keyphrases
- high frequency
- risk factors
- public health
- healthcare
- mental health
- transcranial magnetic stimulation
- liver failure
- oxidative stress
- cardiovascular disease
- mesenchymal stem cells
- cardiovascular events
- type diabetes
- risk assessment
- human health
- climate change
- respiratory failure
- coronary artery disease
- study protocol
- drug induced
- health promotion
- aortic dissection
- replacement therapy
- smoking cessation