Mechanical overload induces TMJ disc degeneration via TRPV4 activation.
Sheng-Jie CuiFu-Jia YangXue-Dong WangZe-Bin MaoYan GuPublished in: Oral diseases (2023)
Our findings suggest TRPV4 plays a pivotal role in the pathogenesis of mechanical overload-induced TMJ disc degeneration and may be a promising target for the treatment of degenerative changes of the TMJ disc.