Therapeutic DNA Vaccine Targeting Mycobacterium tuberculosis Persisters Shortens Curative Tuberculosis Treatment.

Styliani KaranikaTianyin WangAddis YilmaJennie Ruelas CastilloJames T GordyHannah BaileyDarla QuijadaKaitlyn FesslerRokeya TasneenElisa M Rouse SalcidoHarley T HarrisRowan E BatesHeemee TonJacob MezaYangchen LiAlannah D TaylorJean J ZhengJiaqi ZhangJ David PeskeTheodoros KarantanosAmanda R MaxwellEric NuermbergerRichard B MarkhamPetros C Karakousis

Published in: bioRxiv : the preprint server for biology (2024)

A TB vaccine shortens curative drug treatment in mice by eliciting strong TB-protective immune responses and induces similar responses in macaques.

Keyphrases

mycobacterium tuberculosis
immune response
pulmonary tuberculosis
rectal cancer
type diabetes
emergency department
metabolic syndrome
combination therapy
skeletal muscle
hiv infected
cell free
replacement therapy
smoking cessation
nucleic acid