BMP4/ALK3 deficiency leads to Meckel's cartilage truncation mimicking the mandible Tessier 30 cleft.

Jian ZhangChensheng LinYingnan SongJiang Chen

Published in: Oral diseases (2021)

The central hard-tissue loss of both mutant mouse models led to a mandibular symphysis cleft, mimicking the typical sign of the median mandible Tessier 30 cleft in humans.

Keyphrases

mouse model
mesenchymal stem cells
advanced non small cell lung cancer
extracellular matrix
wild type
tyrosine kinase