Systematic evaluation of cancer-specific genetic risk score for 11 types of cancer in The Cancer Genome Atlas and Electronic Medical Records and Genomics cohorts.

Zhuqing ShiHongjie YuYishuo WuXiaoling LinQuanwa BaoHaifei JiaChelsea PerschonDavid DugganBrian T HelfandSiqun L ZhengJianfeng Xu

Published in: Cancer medicine (2019)

Validity of GRS for predicting cancer risk is demonstrated for most types of cancer. If confirmed in larger studies, cancer-specific GRS may have the potential for developing personalized cancer screening strategy.

Keyphrases

papillary thyroid
squamous cell
gene expression
childhood cancer
single cell