Nickel-Catalyzed Asymmetric Hydrocyanation of Allenes.

Jinguo LongJihui GaoXianjie Fang

Published in: Organic letters (2020)

The first catalytic enantioselective hydrocyanation of allenes catalyzed by a (R,R)-Ph-BPE-Ni(0) complex catalyst has been accomplished. Numerous optically active allylic nitriles were obtained in good yield with excellent enantioselectivities (up to 98% ee).

Keyphrases

room temperature
metal organic framework
reduced graphene oxide
ionic liquid
solid state
transition metal