The effect of radiation dose on the onset and progression of radiation-induced brain necrosis in the rat model.
Brad A HartlHtet S W MaKatherine S HansenJulian PerksMichael S KentRuben C FragosoLaura MarcuPublished in: International journal of radiation biology (2017)
The highest dose used in this study led to the shortest time to onset of radiation-induced necrosis, while producing comparable disease progression dynamics after the onset. Therefore, for the radiation-induced necrosis rat model using a linear accelerator, the most optimum results were generated from a dose of 60 Gy.