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Background polygenic risk modulates the association between glaucoma and cardiopulmonary diseases and measures: an analysis from the UK Biobank.

Ajay KolliSayuri SekimitsuJiali WangAyellet SegreDavid FriedmanTobias ElzeLouis R PasqualeJaney WiggsNazlee Zebardast
Published in: The British journal of ophthalmology (2022)
The relations between systemic conditions and glaucoma vary by underlying genetic predisposition to POAG, with larger associations among those who developed glaucoma despite low genetic risk.
Keyphrases
  • optic nerve
  • genome wide
  • gene expression
  • optical coherence tomography