Risk of depression in multiple sclerosis across disease-modifying therapies.

Elisa LonginettiThomas FrisellSimon EnglundJohan ReutforsFang FangFredrik Piehl

Published in: Multiple sclerosis (Houndmills, Basingstoke, England) (2021)

Our results indicate that the choice of DMT is associated with subsequent risk of depression in MS, but further studies are needed to establish whether there is a causal link. Overall, depression and use of antidepressants displayed limited associations with DMT discontinuation and MS relapse.

Keyphrases

multiple sclerosis
depressive symptoms
mass spectrometry
sleep quality
ms ms
major depressive disorder
physical activity
decision making
case control