Association of Hepatic Global DNA Methylation and Serum One-Carbon Metabolites with Histological Severity in Patients with NAFLD.

Zhiwei LaiJunliang ChenChenghe DingKwanshu WongXingyi ChenLiuzhen PuQiangwei HuangXiaolin ChenZijian ChengYan LiuXuying TanHui-Lian Zhu Li Jun Wang

Published in: Obesity (Silver Spring, Md.) (2019)

Patients with NAFLD exhibited lower hepatic levels of global DNA methylation and elevated serum homocysteine concentrations, which are associated with the histological severity of NAFLD.

Keyphrases

dna methylation
genome wide
gene expression
ms ms
copy number