HLA Associations of Intrathecal IgG Production against Specific Viruses in Multiple Sclerosis.

Stephan NeidhartBenjamin VladMarc HiltyKlara Asplund HögelinMario ZieglerErnesto Berenjeno-CorreaIna ReichenPernilla StridhIvan JelcicMohsen KhademiIngrid KockumMireia SospedraFaiez Al NimerRoland MartinIlijas Jelcic

Published in: Annals of neurology (2024)

HLA-DRB1*15:01, the strongest genetic risk factor for MS, and female sex, 1 of the most prominent demographic risk factors for developing MS, predispose in MS/CIS patients for a positive MRZ reaction, the most specific CSF biomarker for MS. ANN NEUROL 2024;95:1112-1126.

Keyphrases

multiple sclerosis
mass spectrometry
ms ms
end stage renal disease
ejection fraction
white matter
newly diagnosed
chronic kidney disease
prognostic factors
genome wide
patient reported outcomes