Single-cell RNA-seq analysis reveals BHLHE40-driven pro-tumour neutrophils with hyperactivated glycolysis in pancreatic tumour microenvironment.

Liwen WangYihao LiuYuting DaiXiaomei TangTong YinChaofu WangTing WangLei DongMinmin ShiJiejie QinMeilin XueYizhi CaoJia LiuPengyi LiuJinyan HuangChenlei WenJun ZhangZhiwei XuFan BaiXiaxing DengChenghong PengHao ChenLingxi JiangSaijuan ChenBaiyong Shen

Published in: Gut (2022)

The dynamic properties of TANs revealed by this study will be helpful in advancing PDAC therapy targeting innate immunity.

Keyphrases

rna seq
single cell
high throughput
stem cells
cell therapy
replacement therapy