Circulating microRNA Profiles in Acetaminophen Toxicity.

Stephanie Pepper CarreiroJames Marvel-CoenRosalind LeeBrittany ChapmanVictor Ambros

Published in: Journal of medical toxicology : official journal of the American College of Medical Toxicology (2019)

Severe cases of acetaminophen toxicity showed two distinct patterns of microRNA elevation which were similar to previous work, while less severe cases were difficult to distinguish from non-acetaminophen-associated cases. Further work is needed to incorporate microRNA profiles into the diagnostic algorithm of acetaminophen toxicity.

Keyphrases

liver injury
drug induced
oxidative stress
early onset
machine learning
deep learning
oxide nanoparticles