Mathematical Models of the Effect of Glucagon on Glycemia in Individuals With Type 2 Diabetes Treated With Dapagliflozin.
Tomoko YamadaHikaru SugimotoKen-Ichi HironakaYasuko MoritaHiroshi MiuraNatsu Otowa-SuematsuYuko OkadaYushi HirotaKazuhiko SakaguchiShinya KurodaWataru OgawaPublished in: Journal of the Endocrine Society (2024)
Treatment with an SGLT2 inhibitor alters the relation between insulin effect and blood glucose concentration, and glucagon effect may account for variation in glycemia among individuals treated with such drugs.