Effect of sarcomere and mitochondria-related mutations on myocardial fibrosis in patients with hypertrophic cardiomyopathy.

Hyemoon ChungYoonjung KimChul-Hwan ParkJong-Youn KimPil-Ki MinYoung Won YoonTae Hoon KimByoung Kwon LeeBum-Kee HongSe-Joong RimHyuck Moon KwonKyung-A LeeEui Young Choi

Published in: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance (2021)

SMs are significantly related to increase in myocardial fibrosis. Although, some HCM patients had pathogenic MMs, it was not associated with an increase in myocardial fibrosis.

Keyphrases

hypertrophic cardiomyopathy
left ventricular
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
heart failure
prognostic factors
liver fibrosis
atrial fibrillation
drug induced
endoplasmic reticulum