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Pharmacokinetics and Safety of Recombinant Human Interleukin-1 Receptor Antagonist GR007 in Healthy Chinese Subjects.

Ran XieYang ZhangNan ZhaoShuang ZhouXin WangWei HanYan YuXia ZhaoYi Min Cui
Published in: European journal of drug metabolism and pharmacokinetics (2019)
The results showed that a single intramuscular injection of 30-150 mg GR007 had good safety and tolerability in healthy Chinese subjects. The results of the evaluation of the safety and pharmacokinetics of GR007 performed in this study support its use as a repeated daily injection in ongoing clinical trials focusing on patients with cancer.
Keyphrases
  • clinical trial
  • recombinant human
  • physical activity
  • ultrasound guided
  • phase ii
  • study protocol