Ambulatory blood pressure monitoring in living kidney donors: What changes in 10 years?
Serkan Feyyaz YalinSinan TrabulusNurhan SeyahiMahir CengizMustafa Erdogan CicikMehmet Riza AltiparmakPublished in: Clinical transplantation (2018)
In renal transplantation, living donations have more significant benefits compared to cadaveric donations. However, a probable increase in blood pressure following donation should also be kept in mind. In this study, we investigated the long-term changes in blood pressure in living kidney donors using ambulatory blood pressure monitoring and we explored the e-GFR and albuminuria/proteinuria measurements at 3 time points. Twenty-eight living kidney donors and 39 healthy individuals were evaluated and compared at the baseline and later at the 10th year. At the 10th year, creatinine levels were higher and eGFR levels were lower in the donors, whereas the systolic and diastolic measurements of the donors and controls and the prevalence of nondipping in the donors and controls were similar. Our study may be underpowered due to its small population size. However, our results at the 10th year follow-up indicated that the risk of hypertension might not seem to have increased in the well-selected donors. In addition, the majority of our donors had preserved their GFR values. Therefore, we can suggest that living kidney donation appears to be safe in well-selected patients over a 10-year time frame.
Keyphrases
- blood pressure
- hypertensive patients
- kidney transplantation
- heart rate
- end stage renal disease
- heart failure
- small cell lung cancer
- blood glucose
- ejection fraction
- chronic kidney disease
- left ventricular
- risk factors
- newly diagnosed
- insulin resistance
- type diabetes
- skeletal muscle
- high resolution
- mass spectrometry
- ultrasound guided
- tyrosine kinase