ITGAM is a risk factor to systemic lupus erythematosus and possibly a protection factor to rheumatoid arthritis in patients from Mexico.
Julian Ramírez-BelloCeli SunGuillermo Valencia PachecoBhupinder SinghRosa Elda Barbosa-CobosMiguel A SaavedraRicardo F López-VillanuevaSwapan K NathPublished in: PloS one (2019)
Our data displayed that ITGAM is a risk factor to SLE in individuals of Mexican population. Concurrently, a risk haplotype in ITGAM confers protection against RA.