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Daikenchuto attenuates visceral pain and suppresses eosinophil infiltration in inflammatory bowel disease in murine models.

Yoko KogureHirosato KandaShenglan WangYongbiao HaoJunxiang LiSatoshi YamamotoKoichi NoguchiYi Dai
Published in: JGH open : an open access journal of gastroenterology and hepatology (2020)
These results suggest that DKT is beneficial for abdominal pain associated with IBD. The anti-inflammatory effect of DKT on IBD may involve inhibition of eosinophils. The mechanism of anti-inflammatory effect of DKT partially differs from that of 5-ASA. Coapplication of DKT and conventional medicine may produce a positive synergy effect for IBD treatment.
Keyphrases
  • anti inflammatory
  • abdominal pain
  • ulcerative colitis
  • chronic pain
  • insulin resistance
  • pain management
  • signaling pathway
  • neuropathic pain
  • combination therapy
  • metabolic syndrome
  • skeletal muscle
  • spinal cord