Solitary chemosensory cells are innervated by trigeminal nerve endings and autoregulated by cholinergic receptors.

Jie DengLi Hui TanMichael A KohanskiDavid W KennedyJohn V BossoNithin D AdappaJames N PalmerJianbo ShiNoam A Cohen

Published in: International forum of allergy & rhinology (2020)

SCCs are innervated by trigeminal nerve endings in healthy turbinate tissue but not in NPs. SCCs express ACh receptors as well as choline acetyltransferase and, in the setting of a type 2 inflammatory environment, denervated SCCs dramatically expand with nicotinic stimulation.

Keyphrases

induced apoptosis
neuropathic pain
peripheral nerve
cell cycle arrest
oxidative stress
endoplasmic reticulum stress
cell death
spinal cord injury
spinal cord
rare case