Standardization of assay representation in the Ontology for Biomedical Investigations.
Randi VitaJie ZhengRebecca C JacksonDamion DooleyJames A OvertonMark A MillerDaniel C BerriosRichard H ScheuermannYongqun Oliver HeHande Küçük McGintyMathias BrochhausenAisyah Yu LinSagar B JainMarcus C ChibucosJohn JudkinsMichelle G GiglioIrene Y FengGully A BurnsMatthew H BrushBjoern PetersChristian J StoeckertPublished in: Database : the journal of biological databases and curation (2021)
The Ontology for Biomedical Investigations (OBI) underwent a focused review of assay term annotations, logic and hierarchy with a goal to improve and standardize these terms. As a result, inconsistencies in W3C Web Ontology Language (OWL) expressions were identified and corrected, and additionally, standardized design patterns and a formalized template to maintain them were developed. We describe here this informative and productive process to describe the specific benefits and obstacles for OBI and the universal lessons for similar projects.