Exploring the Mechanisms of Modified Bu-Shen-Yi-Qi Decoction for COPD-Related Osteoporosis Therapy via Transcriptomics and Network Pharmacology Approach.

Yuanyuan ZhongBin WangWenjing ChenHongying ZhangJing SunJing-Cheng Dong

Published in: Drug design, development and therapy (2023)

MBSYQ is effective in the prevention and treatment of COPD-related osteoporosis, partially achieved by improving oxygen metabolism and activating MAPK and PI3K/AKT pathways.

Keyphrases

pi k akt
signaling pathway
chronic obstructive pulmonary disease
postmenopausal women
lung function
bone mineral density
cell cycle arrest
single cell
mesenchymal stem cells
cystic fibrosis
air pollution
combination therapy
drug induced
replacement therapy