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Low-grade inflammation in persons with recently diagnosed type 2 diabetes: The role of abdominal adiposity and putative mediators.

Sidsel L DomazetThomas B OlesenJacob V StidsenCamilla K SvenssonJens S NielsenReimar W ThomsenNiels JessenPeter VestergaardMette K AndersenTorben HansenCharlotte BrønsVerena H JensenAllan A VaagMichael H OlsenKurt Højlund
Published in: Diabetes, obesity & metabolism (2024)
In persons with recently diagnosed T2D, there was a clear association between abdominal adiposity and low-grade inflammation. A considerable part (20%-40%) of this association was mediated by other factors, with hyperinsulinaemia as a potentially important driver of adiposity-induced inflammation in T2D.
Keyphrases
  • low grade
  • high grade
  • oxidative stress
  • insulin resistance
  • type diabetes
  • diabetic rats
  • weight gain
  • metabolic syndrome
  • high glucose
  • adipose tissue
  • endothelial cells
  • physical activity