A preliminary study on functional activation and connectivity during frustration in youths with bipolar disorder.

Andrew J RossAlexandra L RouleChristen M DeveneyKenneth E TowbinMelissa A BrotmanEllen Leibenluft Wan-Ling Tseng

Published in: Bipolar disorders (2020)

Positive IFG-vmPFC connectivity and striatum-insula decoupling in BD during feedback processing may mediate heightened sensitivity to reward-relevant stimuli. Elevated IFG-PAG/PHG connectivity in BD following frustration may suggest greater recruitment of attention network to regulate arousal and maintain goal-directed behavior.

Keyphrases

resting state
functional connectivity
bipolar disorder
white matter
major depressive disorder
multiple sclerosis