Sleep-related traits and attention-deficit/hyperactivity disorder comorbidity: Shared genetic risk factors, molecular mechanisms, and causal effects.

Marina Xavier Carpena Carolina Bonilla Alicia Matijasevich Thais Martins-Silva Julia Pasqualini Genro Mara Helena Hutz Luis Augusto Rohde Luciana Tovo Rodrigues

Published in: The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry (2021)

Comorbidity between sleep phenotypes and ADHD may be mediated by common genetic factors that play an important role in neuronal signalling pathways. A causal effect of sleep disturbances and short sleep duration on ADHD reinforced their role as predictors of ADHD.

Keyphrases

attention deficit hyperactivity disorder
autism spectrum disorder
risk factors
sleep quality
genome wide
working memory
physical activity
copy number
gene expression
subarachnoid hemorrhage