Acute and durable effect of inhaled hypertonic saline on mucociliary clearance in adult asthma.
William D BennettAllison BurbankMartha AlmondJihong WuAgathe CeppeMichelle HernandezRichard C BoucherDavid B PedenPublished in: ERJ open research (2021)
While MCC was rapidly enhanced during 7% HS treatment there was no effect on MCC at 4 h post-treatment. While these findings may not support aerosolised HS use for maintenance therapy, they do suggest a benefit of treating acute exacerbations in patients with moderate-severe asthma.